Chrome

Step 1

Click first on the customize button

Step 2

Then click on Options

Step 3

Click on the tab Under the Hood

Step 4

Click on Clear browsing data...

Step 5

check the following checkboxes Clear download history, Empty the cache, Delete cookcies an d other site data, Clear saved form data
After you checked the boxes click on Clear browsing data and the cache is cleared.

Force Refresh Chrome

Most times a simple force refresh will do the trick, you can accomplish this with the following key combinations:
Shift + Ctrl + F5

Step by step video on how to refresh your cache

Click the play button to see a step by step guide how to clear the cache for Internet Explorer 7